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This Founder Built Natural GLP-1 Alternative Before the Boom

February 11, 2026
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Opinions expressed by Entrepreneur contributors are their very own.

Key Takeaways

Evolv co-founder Becca McCarthy noticed a large GLP-1 pattern — and constructed a pure different to match it.
She believes urge for food management doesn’t want a prescription, a needle, or a stigma.

Becca McCarthy says she’s at all times been good at recognizing when one thing is about to interrupt into the mainstream. She has spent her profession inside startups, serving to flip early curiosity into actual markets and constructing merchandise earlier than most individuals understand there’s demand for them.

That’s why, a couple of years in the past, when she began listening to individuals in her community speaking about GLP-1 medication, she paid consideration. GLP‑1 medication reminiscent of Ozempic and Zepbound are among the many quickest‑rising prescription medicines within the U.S., with complete GLP‑1 gross sales worldwide estimated at round $50 billion.

However McCarthy was listening to about them lengthy earlier than they turned cultural shorthand. Her in any other case wholesome family and friends had been injecting these medication for weight reduction and maintaining it largely to themselves. Utilizing a drugs designed for diabetes to handle urge for food carried a stigma. It was thought-about dishonest and ran counter to the wellness world’s insistence on clear consuming, self-discipline, and willpower.

That’s when she noticed a chance hole. “I believed, what should you may give you a resolve for this large demand that’s constructing for efficacy from GLP-1 receptor activation with out upsetting the eating regimen and train police, then you might have a large resolution.”

The reply finally turned Evolv, a pure, oral complement designed to imitate the consequences of GLP-1 with out needles, prescriptions, artificial hormones, or the judgment that surrounds prescription drugs.

Associated: This Is How GLP-1 Medication Are Forcing Restaurant Chains to Change Their Menus

A pure resolution

To get there, McCarthy teamed up in 2023 with Dr. Corey Henderson, a molecular biologist who had designed a novel peptide that might work together with GLP1 and GIP receptors in the identical means that the medication do, however in a very pure means with none synthetics. The corporate says the product helps urge for food regulation and metabolic operate by activating the identical pathways that make pharmaceutical GLP-1s so compelling—however via a pure mechanism that begins within the intestine.

They experimented with totally different supply strategies—first a shake, then a dietary complement—and finally landed on a capsule. As soon as they acquired encouraging suggestions from early information, McCarthy dedicated absolutely. “I spotted that is going to alter the world. So I simply went all in,” she says.

Associated: How This Founder Turned ‘Dry January’ Right into a 12 months-Spherical Motion — And Constructed America’s #1 Non-Alcoholic Beer Model

Overcoming hurdles

McCarthy has needed to push via her share of hurdles. One of the vital persistent is being taken critically as a feminine founder. “There’s an inherent bias that we’re up in opposition to, the place it’s very easy for me to be perceived as a extremely competent and investable founder or entrepreneur or boss or chief, but it surely’s very onerous for me to be perceived as likable in that position,” she says.

McCarthy recollects occasions she’s gone to pitch conferences and was mistaken for an admin. One other time, she was turned down solely to observe males get funding with a far inferior concept. It’s onerous,” she says. “It’s not handed to you in the identical means while you’re a feminine.”

One other problem has been the silence that comes with success. Prospects see outcomes, however they don’t essentially wish to clarify how they received them. “Individuals need everyone to suppose it’s as a result of they went to so many Pilates courses,” she says. It’s onerous to construct phrase of mouth when the very factor individuals like most a few product is that nobody is aware of they’re utilizing it.

Regardless of the problem of getting prospects to speak brazenly in regards to the product, McCarthy isn’t dwelling on the advertising and marketing dilemma. She’s centered on serving to individuals handle their urge for food with out requiring a health care provider, a prescription, or a needle. It’s the outcomes that can in the end make the most important distinction. “Individuals simply wish to look higher bare. So once we ship on that, that’s what works.”

Key Takeaways

Evolv co-founder Becca McCarthy noticed a large GLP-1 pattern — and constructed a pure different to match it.
She believes urge for food management doesn’t want a prescription, a needle, or a stigma.

Becca McCarthy says she’s at all times been good at recognizing when one thing is about to interrupt into the mainstream. She has spent her profession inside startups, serving to flip early curiosity into actual markets and constructing merchandise earlier than most individuals understand there’s demand for them.

That’s why, a couple of years in the past, when she began listening to individuals in her community speaking about GLP-1 medication, she paid consideration. GLP‑1 medication reminiscent of Ozempic and Zepbound are among the many quickest‑rising prescription medicines within the U.S., with complete GLP‑1 gross sales worldwide estimated at round $50 billion.



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